IMMUNITY (PART -2)
QUESTIONS
1. Hyperacute rejection is due to ?
(a) Preformed antibodies
(b) Cytotoxic T-lymphocyte mediated injury
(c) Circulating macrophage mediated injury
(d) Endothelitis caused by donor antibodies
2. All are affected in Graft-Versus host reaction ?
(a) Skin
(b) GIT
(c) Liver
(d) Lung
3. Preformed antibodies cause ?
(a) Hyperacute rejection
(b) Acute rejection
(c) Chronic rejection
(d) Acute humoral rejection
4. True about graft versus host disease is ?
(a) Associated with solid organ transplantation
(b) Graft must contains immunocompetent T cell
(c) It is seen in immunosuppressed persons
(d) Also called as Runt disease in animals
5. Acute humoral renal transplant rejection is characterized by the following, except ?
(a) Presence of anti-donor antibodies
(b) Interstitial and tubular mononuclear cell infiltrate
(c) Necrotizing vasculitis
(d) Acute cortical necrosis
6. Transfer of the graft of different species are called as
(a) Isograft
(b) Allograft
(c) Homograft
(d) Xenograft
7. Acute graft versus host disease reaction occurs in all except ?
(a) Liver
(b) Adrenal
(c) Gut
(d) Skin
8. Preformed antibodies cause ?
(a) Hyperacute rejection
(b) Acute rejection
(c) Chronic rejection
(d) Acute humoral rejection
9. Principal cause of death in renal transplant patient is ?
(a) Uraemia
(b) Malignancy
(c) Rejection
(d) Infection
10. Autoimmunity in EBV infection is the result of ?
(a) Molecular mimicry
(b) Polyclonal B cell activation
(c) Expressing sequestrated antigens
(d) Antigenic cross reactivity
11. A 14 yrs. old girl on exposure to cold has pallor of extremities followed by pain and cyanosis. In later ages of life she is prone to develop?
(a) Systemic lupus eryhtematosis
(b) Scleroderma
(c) Rheumatoid arthritis
(d) Hisiocytosis
12. Which is not autoimmune disease?
(a) Systemic Lupus Erythematosis
(b) Grave’s Disease
(c) Myasthenia Gravis
(d) Sickle Cell Disease
13. Which among the following is seen in antiphospholipid antibody syndrome?
(a) Beta 2 microglobulin antibody
(b) Anti nuclear antibody
(c) Anti centromere antibody
(d) Anti glycoprotein antibody
14. Necrotizing lymphadenitis is seen in ?/
(a) Kimura disease
(b) Kikuchi Fujimoto disease
(c) Hodgkin disease
(d) Castelman disease
15. Wire loop lesions are seen in ?
(a) SLE
(b) Diabetic nephropathy
(c) Benign nephrosclerosis
(d) Wegener’s granulomatosis
ANSWERS
1) a 2) d 3) a 4) a 5) b 6) d 7) b 8) a 9) d 10) b 11) b 12) d 3) d 14) b 15) a
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