CARDIOVASCULAR  SYSTEM (PART -1)

 






                                                 QUESTIONS


1. A young female patient came for routine examination. On examination a mid systolic click was found. There is no history of rheumatic heart disease. The histopathological examination is most likely to show which of the following? 

 (a) Myxomatous degeneration and prolapsed of the mitral valve 

(b) Fibrinous deposition on the tip of papillary muscle

 (c) Rupture of chordae tendinae 

(d) Aschoff nodule on the mitral valve 

2. Least chances of infective endocarditis is associated with ?

(a) Mild MS 

(b) Mild MR 

(c) Small ASD 

(d) Small VSD 

3. A 45 yrs old male had severe chest pain and was admitted to the hospital with a diagnosis of acute myocardial infarction. Four days later he died and autopsy showed transmural coagulative necrosis. Which of the following microscopic features will be seen on further examination? 

 (a) Fibroblasts and collagen 

(b) Granulation tissue 

(c) Neutrophilic infiltration surrounding coagulative necrosis 

(d) Granulomatous inflammation

 4. Which one of the following is not included as major criteria in Jones criteria? 

 (a) Pancarditis 

(b) Arthritis 

(c) Subcutaneous nodules

 (d) Elevated ESR 

5. The mechanism of the development of Acute Rheumatic Fever is which of the following? 

 (a) Cross reactivity with exogenous antigen

 (b) Innocent bystander effect

 (c) Due to toxin secretion by streptococci 

(d) Release of pyrogenic cytokines 

6. Cardiac involvement in carcinoid syndrome is characterized by ?

(a) Calcification tricuspid valve 

(b) Intimal fibrosis of right ventricle, tricuspid and pulmonary valve. 

(c) Involvement of the major blood vessels is commonly seen 

(d) Equal involvement of both the sides of the heart 

7. Most friable vegetation is seen in ?

(a) Infective endocarditis 

(b) Libman Sacks endocarditis 

(c) Rheumatic heart disease 

(d) Rheumatoid heart disease 

8. Aschoff’s nodules are seen in ?

 (a) Subacute bacterial endocarditis 

(b) Libman-Sacks endocarditis 

(c) Rheumatic carditis 

(d) Non-bacterial thrombotic endocarditis 

9. A 10-year-old boy, Pappu, died of acute rheumatic fever. All the following can be expected at autopsy except ?

(a) Aschoff’s nodules 

 (b) Rupture of Chordae tendinae 

(c) McCallum patch

 (d) Fibrinous pericarditis 

10. NOT true about ASO titer ?

 (a) May be positive in normal people

 (b) Major Jones’ criteria 

(c) May be negative in post streptococcal glomerulonephritis 

(d) May not be elevated even in presence of Carditis

 11. In mitral valve prolapse syndrome, histopathology of mitral valve shows ?

 (a) Hyaline degeneration 

(b) Elastic degeneration 

(c) Myxomatous degeneration 

(d) Fibrinoid necrosis 

12. Which of the following is not a complication of infective endocarditis?

 (a) Myocardial ring abscess 

(b) Suppurative pericarditis 

(c) Myocardial infarction

 (d) Focal and diffuse glomerulonephritis

 13. Aschoff bodies in Rheumatic heart disease show all of the following features, except ?

 (a) Anitschkow cells 

(b) Epithelioid cells 

(c) Giant cells

 (d) Fibrinoid necrosis 

14. Rheumatic heart disease can be diagnosed on the basis of ?

 (a) Aschoff bodies 

(b) Vegetations along the lines of closure of valves

(c) Endocardial involvement only

 (d) Follows skin and throat infection 

15. Pathognomic feature of acute rheumatic fever is ?

(a) Pericarditis 

 (b) Myocarditis 

(c) Mitral stenosis 

(d) Aschoff’s nodules


                                                ANSWERS


1) a   2) c   3) c   4) d   5) a   6) b   7) a   8) c   9) b   10) b    11) c   12) c   13) b   14) a   15) d