CARDIOVASCULAR SYSTEM (PART -3)
1.All of the following statements regarding atherosclerosis are true except ?
(a) Omega-3 fatty acid (abundant in fish oil) decrease LDL
(b) Atherosclerosis in less important in age more than 45 years age
(c) Cigarette smoking is independent risk factor for M.I
(d) C reactive protein is independent risk factor for M.I
2. Which of the following is the commonest histological finding in benign hypertension?
(a) Proliferative end arteritits
(b) Necrotizing arteriolitis
(c) Hyaline arteriosclerosis
(d) Cystic medial necrosis
3. The presence of stroke, peripheral vascular disease and atherosclerosis is associated with which hormone?
(a) Insulin deficiency
(b) Hyperestrogenemia
(c) Hypothyroidism
(d) Progesterone
4. Most common cause of abdominal aortic aneurysm is?
(a) Atherosclerosis
(b) Syphilis
(c) Trauma
(d) Congenital
5. Hallmark feature of benign HTN is?
(a) Hyaline arteriosclerosis
(b) Cystic medial necrosis
(c) Fibrinoid necrosis
(d) Hyperplastic arteriosclerosis
6. All are seen in malignant hypertension, except ?
(a) Fibrinoid necrosis
(b) Hyaline arteriosclerosis
(c) Necrotizing glomerulonephritis
(d) Hyperplastic arteriosclerosis
7. Recurrent ischemic events following thrombolysis has been pathophysiologically linked to which of the following factors ?
(a) Antibodies to thrombolytic agents
(b) Fibrinopeptide A
(c) Lipoprotein (A)
(d) Triglycerides
8. 70-year-old man has abdominal pain with mass in abdomen. Angiography reveals aneurysm of aorta. Most likely cause is ?
(a) Trauma
(b) Atherosclerosis
(c) Syphilis
(d) Congenital
9. In malignant hypertension hyperplastic arteriosclerosis is seen in all except ?
(a) Heart
(b) Kidney
(c) Pericardial fat
(d) Peripancreatic fat
10. CAD predisposing factors ?
(a) Homocysteinemia
(b) Increased lipoprotein B
(c) Increased fibrinogen
(d) Increased HDL
(e) Increased plasminogen activator inhibitors
11. Features of essential hypertension ?
(a) Concentric hypertrophy of LV
(b) Increased heart size
(c) Increased size of the heart muscles
(d) Myohypertrophy
(e) Myohyperplasia
12. In atherosclerosis, increased LDL in monocyte macrophage is due to?
(a) LDL receptors on macrophage
(b) LDL receptors on endothelium
(c) Lipids in LDL get auto-oxidized
(d) All of the above
13. Which of the following is the least common site of atherosclerotic lesions?
(a) Aortic bifurcation
(b) Pulmonary arterial trunk
(c) Common carotid artery
(d) Middle cerebral artery
14. Vascular pathology of benign hypertension includes ?
(a) Segmental fibrinoid necrosis
(b) Hyaline arteriosclerosis
(c) Periarteritis
(d) Loss of internal elastic lamina
15. Accelerated phase of hypertension is characterized microscopically by ?
(a) Fibrinoid necrosis of arteriolar wall
(b) Hyaline arteriosclerosis
(c) Elastosis of the intima
(d) Marked calcification of the media
16. Most common site of atherosclerotic aneurysm is ?
(a) Coronary artery
(b) Renal artery
(c) Arch of aorta
(d) Abdominal aorta
17. Monckeberg’s calcific sclerosis affects the medium sized muscular arteries by involving the structure of ?
(a) Intima
(b) Media
(c) Adventitia
(d) All of the above
ANSWERS
1) b 2) c 3) a 4) a 5) a 6) b 7) c 8) b 9) a 10) a 11) a 12) c 13) b 14) b 15) a 16) d 17) b
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