CELL INJURY (PART -1)

The Question are Based on Exam Pattern and The Question Is Very Useful For Practice MCQ.


                                                        
                                                                      QUESTIONS


1. In apoptosis, cytochrome C acts through?

(a) Apaf 1 

(b) Bcl-2 

(c) FADD 

(d) TNF

2. Cells most sensitive to hypoxia are?

(a) Myocardial cells 

(b) Neurons 

(c) Hepatocytes 

(d) Renal tubular epithelial cells 

3. In cell death, myelin figures are derived from?

(a) Nucleus

 (b) Cell membrane 

(c) Cytoplasm 

(d) Mitochondria

4. Irreversible cell injury is characterised by which of the following? 

(a) Mitochondrial densities 

(b) Cellular swelling

(c) Blebs 

(d) Myelin figures

5. Coagulative necrosis as a primary event is most often seen in all except? 

(a) Kidneys 

(b) CNS 

(c) Spleen 

(d) Liver

6.Organelle that plays a pivotal role in apoptosis? 

(a) Endoplasmic reticulum 

(b) Golgi complex 

(c) Mitochondria 

(d) Nucleus

7. Intracellular calcification begins in which of the following organelles?

 (a) Mitochondria 

(b) Golgi body 

(c) Lysososme 

(d) Endoplasmic reticulum

 8.Liquefactive necrosis is seen in?

(a) Heart 

(b) Brain 

(c) Lung 

(d) Spleen

9. Following is seen in both apoptosis and necrosis?

(a) Both may be physiological 

(b) Both may be pathological 

(c) Inflammation 

(d) Intact cell membrane

10. Following gene when mutated protects tumor cells from Apoptosis ?

(a) BCL – 2 

(b) BRCA 

(c) RB 

(d) TGF – β

11. Which of the following is not seen is apoptosis? 

(a) Chromatin condensation 

 (b) DNA fragmentation 

(c) Inflammation 

(d) Cell membrane shrinkage

12. Which of the following induces apoptosis in a cell? 

(a) Oleic acid  

(b) Isoprenoids 

(c) Myristic acid 

(d) Glucocorticoids

                                                     ANSWERS


1) a   2) b   3) b    4) a    5) b   6) c   7)  a    8) b   9) b   10) a   11) c   12) d