INFLAMMATION (PART- 3)




                                                  QUESTIONS


1. All of the following are a family of selectin except

 (a) P selectin 

(b) L selectin 

(c) A selectin 

(d) E selectin 

2. Most important for diapedesis? 

(a) PECAM 

(b) Selectin 

(c) Integrin

 (d) Mucin like glycoprotein 

 3. In acute inflammation the tissue response consists of all except ?

(a) Vasodilatation

 (b) Exudation 

(c) Neutrophilic response 

(d) Granuloma formation

 4. The function common to neutrophils, monocytes, and macrophages is ?

 (a) Immune response is reduced 

(b) Phagocytosis 

(c) Liberation of histamine

 (d) Destruction of old erythrocytes

5. Fever occurs due to ?

 (a) IL 1

 (b) Endorphin 

(c) Enkephalin 

(d) Histamine 

 6. E cadherin gene deficiency is seen in ?

 (a) Gastric cancer

 (b) Intestinal cancer 

(c) Thyroid cancer 

(d) Pancreatic cancer 

7. Cell-matrix adhesions are mediated by? 

(a) Cadherins

 (b) Integrins 

(c) Selectins 

(d) Calmodulin 

 8. Pro inflammatory Cytokines include all ofthe following except  ?

(a) Interleukin 1

 (b) Interleukin-10 

(c) Interleukin 6 

(d) TNF- Alpha

9. The most important source of histamine ?

 (a) Mast cells 

(b) Eosinophil 

(c) Neutrophil 

(d) Macrophages 

 10. Following injury to a blood vessel, immediate haemostasis is achieved by which of the following?

(a) Fibrin deposition 

(b) Vasoconstriction 

(c) Platelet adhesion 

(d) Thrombosis 

11. PAF causes all except ?

(a) Bronchoconstriction 

(b) Vasoconstriction

 (c) Decreased vascular permeability 

(d) Vasodilation 

12. Eosinophils are activated by ?

(a) IL1 

(b) IL5

 (c) IL4 

(d) IL6 

13. Both antibody dependent and independent complement pathway converge on which complement component? 

(a) C3

 (b) C5

 (c) C1q

 (d) C8

 14. Cryoprecipitate is rich in which of the following clotting factors? 

(a) Factor II

 (b) Factor V

 (c) Factor VII 

(d) Factor VIII

 15. Prostaglandins are synthesized from ? 

(a) Linoleic acid 

(b) Linolenic acid 

(c) Arachidonic acid 

(d) Butyric acid 

16. Which chemical mediator is an arachidonic acid metabolite produced by cyclo-oxygenase pathway? 

(a) LXA4 

(b) LXB4

 (c) 5HETE

 (d) PGH2 

17. Procalcitonin is used as marker of ?

(a) Cardiac dysfunction in acute coronary syndrome 

(b) Menstrual periodicity

 (c) Pituitary function 

(d) Sepsi


                                                    ANSWERS



1) c   2) a   3) d   4) b   5) a   6) a   7) b   8) b   9) a   10) b   11) c  12) b   13) a   14) d   15) c   16) d   

17) d